Antoanella Calame, MD


r. Antoanella Calame is a fellowship-trained dermatopathologist who combines the latest scientific advances with the clinical art of medicine. She has expertise in Mohs surgery and is board certified in dermatology. Dr. Calame welcomes new patients.
Dr. Antoanella Calame received her MD degree from University of California, San Diego (UCSD) after graduating Summa Cum Laude from California Lutheran University. She completed her residency in dermatology at UCSD, followed by a dermatopathology fellowship at University of Texas, Southwestern (UTSW) in Dallas, Texas, where she trained with Dr. Clay Cockerell, one of the world leaders in the field of dermatopathology. Dr. Calame is board certified in dermatology and dermatopathology and holds over thirty active state medical licenses. She is the author of a book on cutaneous manifestations of HIV disease and has published numerous peer reviewed scientific papers. Dr. Calame is an invited speaker at local and national conferences every year. She has a special interest in melanoma and melanocytic lesions and is actively involved with the newest clinical and molecular techniques used in the diagnosis and prognosis of cutaneous melanoma. Dr. Calame is the founder and director of Compass Dermatopathology and Poway Dermatology. She practices dermatopathology full time and spends a limited time seeing dermatology patients. Dr. Calame teaches dermatology and dermatopathology to the UCSD and Navy dermatology residents, as well as dermatology and pathology residents who come to rotate with her from all over the United States and the world. She has received the annual Excellence in Teaching Award from UTSW and UCSD four times. Dr. Calame’s interests outside of work include tennis, yoga, camping, and spending time with her family.

Antoanella Calame, MD
Board Certified in Dermatology and Dermatopathology

Work Experience:

  • Director, Owner, and Chief Dermatopathologist, Compass Dermatopathology, Inc., July 2010 – Present
  • Dermatologist, Owner, Dermatology Center of La Jolla and Poway Dermatology, January 2011 – Present
  • Dermatology Section Chief, Scripps Memorial Hospital, La Jolla, CA, July 2013 – Present
  • Volunteer Clinical Professor, UC San Diego, Department of Dermatology, June 2014 – Present
  • Assistant Clinical Professor, UC San Diego, Division of Dermatology, October 2012 – June 2014
  • Staff Dermatologist, Veterans Affairs Medical Center, La Jolla, CA, November 2011 – June 2014
  • Assistant Clinical Professor, University of Texas, Southwestern, Dept. of Dermatology, 2008 – 2010
  • Associate Dermatopathologist and Assistant Dermatopathology Fellowship Program Director, Cockerell and Associates, Dallas, Texas, 2008 – 2010


    • Dermatopathology Fellowship, University of Texas, Southwestern, 2007-2008
    • Dermatology Residency, Univ. of California, San Diego, Division of Dermatology, 2004-2007
    • Mohs/Research Fellowship, Univ. of California, San Diego, Division of Dermatology, 2003-2004
    • Internal Medicine Internship, Univ. of California, San Diego, Department of Medicine, 2002-2003
    • M.D. degree, Univ. of California, San Diego, School of Medicine, Class Rank Highest Percentile June 2002
    • Bachelor of Science, Biochemistry and Molecular Biology, California Lutheran University, Summa Cum Laude, June 1996

    Board Certification and Licensure:

    • Board Certified by the American Board of Dermatology in Dermatology and Dermatopathology
    • Medical Licenses: CA, AZ, CO, CT, DC, DE, FL, GA, IA, ID, IL, LA, MD, MI, MN, MS, MT, NC, NE, NJ, NM, NY, OH, OR, PA, RI, SC, TN, TX, UT, VA, WA, WI, WY

    Research Experience:

    • University of California, San Diego, Division of Dermatology 07/03-06/04
    • Role of cathelicidin in the pathogenesis of rosacea – Richard Gallo, MD, PhD
    • Mohs Surgery – Constance Nagi, MD
    • University of California, San Diego, School of Medicine, 08/98 – 06/02
    • Screening of Human CMV Infected Fibroblasts for Propagation of a Chromosome Break, June 1999 – December 1999, Dr. Deborah Spector, Department of Biology, UCSD School of Medicine
    • Effects of Oat Derived Beta-Glucan on Wound Healing, Clinical Trial, April 2001 to May 2002, Dr. Constance Nagi, Chair, Department of Dermatology, UCSD School of Medicine
    • Amgen, Inc. – Research Associate II, Molecular and Cell Biology Department, 06/96-08/98
    • Development of non-radioactive mRNA quantification assay (RT-PCR ELISA)
    • Cloning of novel cytokine receptor gene
    • Erythropoietin expression in MCAT-1 knock out mice
    • Development of assay for the detection and quantification of transgenes in zebra fish
    • Determination of tyrosine kinase mRNA levels following treatment with antisense oligos in cultured embryonic murine mandibles

    Honors and Selected Awards:

    • Robert W. Goltz Excellence in Teaching Award – 2014 and 2012, UCSD Division of Dermatology
    • Outstanding Teaching Awards – June 2010 (Faculty of the Year) and June 2008 (Fellow of the Year), Department of Dermatology, University of Texas, Southwestern, Dallas, Texas
    • Merck Award for Best Medical Students – June 2002, UCSD School of Medicine
    • Dean of Student’s Award For Contributions to the Medical School Community, UCSD School of Medicine
    • NIH Grant Recipient – For Studying the Propagation of a Chromosome Break in Human Cytomegalovirus Infected Fibroblasts, June 1999, UCSD SOM
    • Dean’s Award (Valedictorian), June 1996, California Lutheran University


    • American Academy of Dermatology (Leadership Forum graduate; former member of the Residents and Fellows Committee and Healthcare Finance Committee)
    • San Diego Dermatologic Society – President (2011-2013)
    • American Medical Association, Pacific Dermatologic Association, Noah Worcester Dermatologic Association


    • Cutaneous Manifestations of HIV Disease – Clay Cockerell and Antoanella Calame, Manson Publishing Ltd, 1st edition, 2012


    • Nodular Basal Cell Carcinoma. Morrel T, Chung G, Calame A. JDNA Dermpath Insight. 2015 Sept; 7(5):293-5, in print.
    • Another Great Imitator: Allergic Contact Dermatitis Differential Diagnosis, Clues to Diagnosis, Histopathology, and Treatment. So J, Hamstra A, Calame A, Hamann C, Jacob S. Springer Int’l Publishing 2015.
    • Ecthyma Gangrenosum- Like Lesions Secondary to Methicillin-Sensitive Staphylococcus Aureus in an Immunocompetent Pediatric Patient. Song S, Matiz C, Calame A, Krakowski A, Tom W, Friedlander S, Pediatric Dermatology. 2015 July, in print.
    • Diffuse erythema and dry scales in a female infant. X-linked dominant Conradi-Hunermann-Happle (CHH) syndrome. Ali L, Ricotti C, Li L, Calame A, Brouha B, Helm T, Cockerell C. Am J Dermatopathol. 2011 May;33(3):316, 331.
    • Sweet’s syndrome and subacute thyroiditis: an unrecognized association? Richard J, Lazarte S, Calame A, Lingvay I. Thyroid. 2010 Dec;20(12):1425-6.
    • Acquired dermal melanocytosis of the hand at the site of treated psoriasis. KelleyBP, DohertySD, Calame A, Hsu S. Dermatol Online J. 2009 Dec 15;15(12):2.
    • Granular cell atypical fibroxanthoma: case report and review of the literature. Wright NA, Thomas CG, Calame A, Cockerell CJ. J Cutan Pathol. 2009 Mar 31.
    • Edematous nodules on the extremities of a febrile patient: cutaneous cryptococcosis. Boswell JS, Bardan A, McDonald H, Pandya AG. Arch Dermatol. 2008 Dec;144(12):1651.
    • Increased serine protease activity and cathelicidin promotes skin inflammation in rosacea. Yamasaki K, Di Nardo A, Bardan A, Murakami M, Ohtake T, Coda A, Dorschner RA, Bonnart C, Descargues P, Hovnanian A, Morhenn VB, Gallo RL. Nature Medicine 2007 Aug;13(8):975-80.
    • Cutaneous defense mechanisms by antimicrobial peptides. Braff MH, Bardan A, Nizet V, Gallo RL. Journal of Investigative Dermatology. 2005 Jul;125(1):9-13. Review.
    • Antimicrobial Peptides and the Skin, Antoanella Bardan, MD, Victor Nizet, MD, Richard Gallo, MD, PhD, Expert Opinions in Biological Therapy. 2004 Apr;4(4):543-9

    Selected Book Chapters:

    • Cutaneous Manifestations of HIV Disease. Crystal Thomas, MD, Antoanella Calame, MD, Clay Cockerell, MD. In: Sauer’s Manual of Skin Disease, Lippincott Williams & Wilkins, 10th edition, 2010
    • Cutaneous Manifestations of HIV Disease. Crystal Thomas, MD, Antoanella Calame, MD, Clay Cockerell, MD. In: Hall’s Manual of Skin As a Marker of Underlying Disease; 1st edition, 2010
    • Dermatologic Signs of Systemic Disease. Antoanella Bardan, MD, Tissa Hata, MD. Book Chapter – Harris and Weissman: Head and Neck Manifestations of Systemic Disease. Submitted October 2005, Published 2007

    Selected Invited Lectureship Presentations:

    • Course Director, Basic Dermatopathology Self-Assessment Course 2013, 2014, 2015 American Association of Dermatology (AAD) Annual Meetings
    • Advanced Dermatopathology Self-Assessment Course, 2014, 2015 AAD Annual Meetings
    • Molecular Techniques for Diagnosis and Prognosis of Melanoma, SDDSS Meeting, 2015
    • Molecular Diagnostics in Melanoma; Basal and Squamous Cell Carcinoma Histology; Cutaneous Manifestations of Internal Malignancies and Other Paraneoplastic Syndromes, Practical Dermatology and Dermatopathology Symposium, Vail, CO 2014, 2015
    • Histopathology of Normal Skin, Histopathology of Unusual Tumors, Staining and IHC Pearls for Mohs Surgeons, Fundamentals in Mohs Surgery Course, 2012, 2013, 2014
    • Frozen Section Immunohistochemistry in Dermatopathology and Mohs Surgery, Pathology Leaders Webinar Series, March 2013
    • Practical Approaches to Panniculitis, Annual European Academy of Dermatology and Venereology (EADV) Meeting, September 2012
    • Course Co-director, Basic Dermatopathology Self-Assessment 2012 AAD Annual Meeting, Speaker 2008-2011
    • Dermatopathology and Frozen Section Immunohistochemistry in Mohs Surgery, Annual Romanian Dermatologic Society Meeting, Webcast Lecture, 2012
    • Advances in Melanoma Diagnosis – Keynote Speaker, Leica Symposia 2010, San Diego, CA and Houston, TX
    • Melanoma Management and Dermatopathology Grand Rounds Lectures at the Annual SCOPE (Skin Curriculum Overview for Physician Extenders) meetings – 2008 Atlanta, GA, 2009, 2010 Dallas, TX
    • Dermatology Updates and Procedures – TOPICS (Annual Internal Medicine Conference, San Diego, CA)
    • Introduction to Mohs Surgery – Annual Romanian Dermatologic Society Meeting, Bucharest, Romania, June 2006
    • Session, November 1999