Antoanella Calame, MD


r. Antoanella Calame is a fellowship-trained dermatopathologist who combines the latest scientific advances with the clinical art of medicine. She has expertise in Mohs surgery and is board certified in dermatology. Dr. Calame welcomes new patients.
Dr. Antoanella Calame received her MD degree from University of California, San Diego (UCSD) after graduating Summa Cum Laude from California Lutheran University. She completed her residency in dermatology at UCSD, followed by a dermatopathology fellowship at University of Texas, Southwestern (UTSW) in Dallas, Texas, where she trained with Dr. Clay Cockerell, one of the world leaders in the field of dermatopathology. Dr. Calame is board certified in dermatology and dermatopathology and holds over thirty active state medical licenses. She is the author of a book on cutaneous manifestations of HIV disease and has published numerous peer reviewed scientific papers. Dr. Calame is an invited speaker at local and national conferences every year. She has a special interest in melanoma and melanocytic lesions and is actively involved with the newest clinical and molecular techniques used in the diagnosis and prognosis of cutaneous melanoma. Dr. Calame is the founder and director of Compass Dermatopathology, Poway Dermatology and SkyMD. She practices dermatopathology full time and spends a limited time seeing dermatology patients. Dr. Calame teaches dermatology and dermatopathology to the UCSD and Navy dermatology residents, as well as dermatology and pathology residents who come to rotate with her from all over the United States and the world. She has received the annual Excellence in Teaching Award from UTSW and UCSD four times. Dr. Calame’s interests outside of work include tennis, yoga, camping, and spending time with her family.

Antoanella Calame, MD
Board Certified in Dermatology and Dermatopathology

Work Experience:

  • Chief Dermatopathologist and Owner, Compass Dermatopathology, Inc., July 2010 – Present
  • Teledermatology Provider and Owner, SkyMD, Inc. – 2017 – Present
  • Dermatologist, Owner, Calame Dermatology and Poway Dermatology, 2011 – Present
  • Dermatology Section Chief, Scripps Memorial Hospital, La Jolla, CA, July 2013 – December 2018
  • Volunteer Clinical Professor, UC San Diego, Department of Dermatology, June 2014 – Present
  • Volunteer Dermatologist (WOC), Veterans Affairs Medical Center, La Jolla, CA, June 2014 – Present
  • Consultant, Google Research, Google, Inc., 2016 – 2017
  • Assistant Clinical Professor, UC San Diego, Division of Dermatology, October 2012 – June 2014
  • Staff Dermatologist, Veterans Affairs Medical Center, La Jolla, CA, November 2011 – June 2014
  • Assistant Clinical Professor, University of Texas, Southwestern, Dept. of Dermatology, 2008 – 2010
  • Associate Dermatopathologist and Assistant Dermatopathology Fellowship Program Director, Cockerell and Associates, Dallas, Texas, 2008 – 2010
  • Research Associate II, Amgen, Inc., Thousand Oaks, CA, 1996 – 1998


  • Dermatopathology Fellowship, University of Texas, Southwestern, 2007-2008
  • Dermatology Residency, Univ. of California, San Diego, Division of Dermatology, 2004-2007
  • Mohs/Research Fellowship, Univ. of California, San Diego, Division of Dermatology, 2003-2004
  • Internal Medicine Internship, Univ. of California, San Diego, Department of Medicine, 2002-2003
  • M.D. degree, Univ. of California, San Diego, School of Medicine, Class Rank Highest Percentile June 2002
  • Bachelor of Science, Biochemistry and Molecular Biology, California Lutheran University, Summa Cum Laude, June 1996

Board Certification and Licensure:

  • Board Certified by the American Board of Dermatology in Dermatology and Dermatopathology
  • Medical Licenses: CA, AZ, CO, CT, DC, DE, FL, GA, HI, IA, ID, IL, LA, MD, MI, MN, MS, MT, NC, NE, NJ, NM, NV, NY, OH, OR, PA, RI, SC, TN, TX, UT, VA, WA, WI, WY

Honors and Selected Awards:

  • Robert W. Goltz Excellence in Teaching Award – 2016, 2014, and 2012, UCSD Division of Dermatology
  • Outstanding Teaching Awards – June 2010 (Faculty of the Year) and June 2008 (Fellow of the Year), Department of Dermatology, University of Texas, Southwestern, Dallas, Texas
  • Merck Award for Best Medical Students – June 2002, UCSD School of Medicine
  • Dean of Students Award For Contributions to the Medical School Community, UCSD School of Medicine
  • NIH Grant Recipient – For Studying the Propagation of a Chromosome Break in Human Cytomegalovirus Infected Fibroblasts, June 1999, UCSD SOM
  • Dean’s Award (Valedictorian), June 1996, California Lutheran University


  • American Academy of Dermatology (Leadership Forum and Advanced Leadership Forum graduate; former member of the Residents and Fellows Committee and Healthcare Finance Committee)
  • San Diego Dermatologic Society – President (2011-2013), Member (2010-present)
  • American Medical Association, California Dermatologic Association, Pacific Dermatologic Association, Noah Worcester Dermatologic Association (Board of Directors)

Books: Cutaneous Manifestations of HIV Disease – Clay Cockerell and Antoanella Calame, Manson Publishing Ltd, 1st edition, 2012

Scientific Publications:

  • Basal Cell Carcinoma Originating in a Tattoo: Case Report and Review of an Uncommon Complication in Tattoo
    Recipients. Abudu B, Erickson CP, Calame A, Cohen PR. Dermatol Pract Concept. 2019 Oct 31;9(4):265-270

  • Melanoacanthoma Masquerading as Melanoma: Case Reports and Literature Review. Gutierrez N, Erickson CP,
    Calame A, Sateesh BR, Cohen PR. Cureus. 2019 Jun 25;11(6):e4998

  • Osteoma Cutis Associated with Nevus Sebaceus: Case Report and Review of Cutaneous Osteoma-associated
    Skin Tumors (COASTs). Azzam MJ, Beutler BD, Calame A, Erickson CP, Cohen PR. Cureus. 2019 Jun 20;11(6):e4959

  • Melanoma Following In Vitro Fertilization: Co-incident or Coincidence? Cohen PR, Erickson CP, Sateesh BR,
    Uebelhoer NS, Calame A. Cureus. 2019 Jun 7;11(6):e4857. doi: 10.7759/cureus.4857

  • Pigmented Actinic Keratosis: Case Report and Review of an Uncommon Actinic Keratosis Variant that can
    Mimic Melanoma. Abudu B, Calame A, Cohen PR. Cureus. 2019 May 22;11(5):e4721. doi: 10.7759/cureus.4721

  • Atrophic Dermatofibroma: A Comprehensive Literature Review. Cohen PR, Erickson CP, Calame A. Dermatol Ther
    (Heidelb). 2019 Sep;9(3):449-468. doi: 10.1007/s13555-019-0309-y. Epub 2019 Jul 23. Review.

  • Osteoma Cutis: An Adverse Event Following Tattoo Placement. Basu P, Erickson CP, Calame A, Cohen PR. Cureus.
    2019 Mar 26;11(3):e4323. doi: 10.7759/cureus.4323.

  • Painful tumors of the skin. Cohen PR, Erickson CP, Calame A. Clinical, Cosmetic and Investigational
    Dermatology, Vol 2019:12 Pages 123-132.

  • Keratoacanthomatous Changes: Unifying the Histologic Spectrum of Actinic Granuloma. Harb JN, Kalen JE,
    Hsu S, Diwan AH, Calame A, Motaparthi K. Am J Dermatopathol. 2018 Oct; 40(10):762-766.

  • Histologic and Clinical Changes in Vulvovaginal Tissue After Treatment With a Transcutaneous
    Temperature-Controlled Radiofrequency Device. Vanaman Wilson MJ, Bolton J, Jones IT, Wu DC, Calame
    A, Goldman MP. Dermatol Surg. 2018 May; 44(5):705-713.

  • A single-center clinical trial to evaluate the efficacy of a tripeptide/hexapeptide antiaging regimen. Widgerow
    AD, Jiang LI, Calame A. J Cosmet Dermatol. 2018 Mar 4.

  • Pediatric penile porokeratosis: A case report. Bari O, Calame A, Marietti-Shepherd S, Barrio VR. Pediatr
    Dermatol. 2018 Mar;35(2):e103-e104 Epub 2018 Jan 16.

  • Atypical Fibroxanthoma in a 13-Year-Old Guatemalan Girl with Xeroderma Pigmentosum. Chappell, A. G.,
    Chase, E. P., Chang, B., Cunningham, E., Mihm, F., Calame, A., Fudem, G. and Cunningham, B. (2016),
    Pediatr Dermatol, 33: e228–e229.

  • Evaluation of the in vivo effects of various laser, light, or ultrasound modalities on human skin treated with a
    collagen and polymethylmethacrylate microsphere dermal filler product. Wu DC, Karnik J, Margarella T,
    Nguyen VL, Calame A, Goldman MP. Lasers Surg Med. 2016 Nov; 48(9):811-819

  • Use of Oral Plypodium Leucotomos Extract in Chronic Photoinduced Hypersensitivity Dermatitis. Luber AJ,
    Calame A, Jacob SE. Skinmed. 2016 Feb 1;14(1)62-3.

  • Late-onset granuloma formation after poly-l-lactic acid injection. Storer M, Euwer R, Calame A, Kourosh
    AS. JAAD Case Rep. 2016 Feb 1;2(1):54-6.

  • Atypical Fibroxanthoma in a 13-Year-Old Guatemalan Girl with Xeroderma Pigmentosum. Chappell AG,
    Chase EP, Chang B, Cunningham E, Mihm F, Calame A, Fudem G, Cunningham B. Pediatr Dermatol. 2016
    May:33(3):e228-9. Epub 2016 Apr 4.

  • Psoriasiform eruptions during Kawasaki disease (KD): A distinct phenotype. Haddock ES, Calame A,
    Shimizu C, Tremoulet AH, Burns JC, Tom WL. J Am Acad Dermatol. 2016 Jul;75(1):69-76.

  • Ecthyma Gangrenosum- Like Lesions Secondary to Methicillin-Sensitive Staphylococcus Aureus in an
    Immunocompetent Pediatric Patient. Song S, Matiz C, Calame A, Krakowski A, Tom W, Friedlander S,
    Pediatric Dermatology. 2015 Nov;32(6)

  • Diffuse erythema and dry scales in a female infant. X-linked dominant Conradi-Hunermann-Happle (CHH)
    syndrome. Ali L, Ricotti C, Li L, Calame A, Brouha B, Helm T, Cockerell C. Am J Dermatopathol. 2011
    May;33(3):316, 331.

  • Sweet’s syndrome and subacute thyroiditis: an unrecognized association? Richard J, Lazarte S, Calame A,
    Lingvay I. Thyroid. 2010 Dec;20(12):1425-6.

  • Acquired dermal melanocytosis of the hand at the site of treated psoriasis. KelleyBP, DohertySD, Calame A,
    Hsu S. Dermatol Online J. 2009 Dec 15;15(12):2.

  • Granular cell atypical fibroxanthoma: case report and review of the literature. Wright NA, Thomas CG,
    Calame A, Cockerell CJ. J Cutan Pathol. 2009 Mar 31.

  • Edematous nodules on the extremities of a febrile patient: cutaneous cryptococcosis. Boswell JS, Bardan A,
    McDonald H, Pandya AG. Arch Dermatol. 2008 Dec;144(12):1651.

  • Increased serine protease activity and cathelicidin promotes skin inflammation in rosacea. Yamasaki K, Di
    Nardo A, Bardan A, Murakami M, Ohtake T, Coda A, Dorschner RA, Bonnart C, Descargues P, Hovnanian
    A, Morhenn VB, Gallo RL. Nature Medicine 2007 Aug;13(8):975-80.

  • Cutaneous defense mechanisms by antimicrobial peptides. Braff MH, Bardan A, Nizet V, Gallo RL. Journal
    of Investigative Dermatology. 2005 Jul;125(1):9-13. Review.

  • Antimicrobial Peptides and the Skin, Antoanella Bardan, MD, Victor Nizet, MD, Richard Gallo, MD, PhD,
    Expert Opinions in Biological Therapy. 2004 Apr;4(4):543-9

Selected Invited Lectureship Presentations:

  • Course Director, Basic Dermatopathology Self-Assessment Course 2013, 2014, 2015, Lecturer 2016, 2017, 2018, 2019 American Academy of Dermatology (AAD) Annual Meetings
  • Advanced Dermatopathology Self-Assessment Course, 2014, 2015, 2016, 2017AAD Annual Meetings
  • Molecular Techniques for Diagnosis and Prognosis of Melanoma, SDDSS Meeting, 2015, Noah Worcester 2016
  • Molecular Diagnostics in Melanoma; Pediatric Dermatopathology; Basal and Squamous Cell Carcinoma Histology; Cutaneous Manifestations of Internal Malignancies and Other Paraneoplastic Syndromes, Practical Dermatology and Dermatopathology Symposium, Vail, Colorado 2014, 2015, 2016, 2017, 2019
  • Histopathology of Normal Skin, Histopathology of Unusual Tumors, Staining and IHC Pearls for Mohs Surgeons, Fundamentals in Mohs Surgery Course, 2012, 2013, 2014, 2015, 2016, 2017, 2018, 2019
  • Frozen Section Immunohistochemistry in Dermatopathology and Mohs Surgery, Pathology Leaders Webinar Series, March 2013
  • Practical Approaches to Panniculitis, Annual European Academy of Dermatology and Venereology (EADV) Meeting, September 2012
  • Course Co-director, Basic Dermatopathology Self-Assessment 2012 AAD Annual Meeting, Speaker 2008-11, 2016
  • Dermatopathology and Frozen Section Immunohistochemistry in Mohs Surgery, Annual Romanian Dermatologic Society Meeting, Webcast Lecture, 2012
  • Advances in Melanoma Diagnosis – Keynote Speaker, Leica Symposia 2010, San Diego, CA and Houston, TX

Selected Book Chapters:

  • Cutaneous Manifestations of HIV Disease. Crystal Thomas, MD, Antoanella Calame, MD, Clay Cockerell, MD. In: Sauer’s Manual of Skin Disease, Lippincott Williams & Wilkins, 10th edition, 2010
  • Cutaneous Manifestations of HIV Disease. Crystal Thomas, MD, Antoanella Calame, MD, Clay Cockerell, MD. In: Hall’s Manual of Skin As a Marker of Underlying Disease; 1st edition, 2010
  • Dermatologic Signs of Systemic Disease. Antoanella Bardan, MD, Tissa Hata, MD. Book Chapter – Harris and Weissman: Head and Neck Manifestations of Systemic Disease. Submitted October 2005, Published 2007